TIMELY-PLEX — Early vs. Rescue Plasma Exchange

Treatment of Inflammatory Myelitis and Optic Neuritis with Early vs. Rescue Plasma Exchange (TIMELY-PLEX) Mayo IRB #: 25-000657 | 07/2025–07/2026 Sponsor: Mayo Clinic Role: Co-Investigator – Maja Kostic, MD, MMSc, PhD Open-label, rater-blinded, pragmatic randomized controlled trial evaluating early versus rescue therapeutic plasma exchange for visual outcomes in severe optic neuritis and neurologic disability outcomes in severe transverse myelitis.